POTENTIALLY ACTIVE METAL OF COBALT, COPPER AND ZINC COMPLEXES DERIVED FROM SCHIFF BASE LIGAND OF 3-ETHOXY-2-HYDROXY-BENZALDEHYDE AND ANILINE FOR THEIR ANTICANCER ACTIVITY

New Schiff base transition metal complexes derived from 3-ethoxy-2-hydroxy-benzaldehyde and aniline were characterized by magnetic susceptibility measurements, molar conductance, MS, FT-IR, 1H-NMR, 13C-NMR, Absorbance EPR spectra. The spectral evidences clearly showed that all the chelates distorted octahedral geometry except Zn(II) complex which exist square planar geometry. Electron Spin Resonance (ESR) spectrum of [CuL] was coinciding with proposed geometries other reported complexes. All synthesized compounds studied for anticancer studies MTT method using Hela cells. From activities, observed IC50 values are significantly higher than standard Cis-platin. cytotoxicity tested against cell line pursued their order Co(II) > Cu(II) ligand. Among them, cytotoxic activity base.